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USMLE

[NEEDS EXPERT REVIEW] Which class of drugs works primarily by inhibiting the enzyme HMG-CoA reductase?

Correct answer

A. Statins

Explanation

Statins (e.g., atorvastatin, simvastatin) lower cholesterol synthesis by inhibiting HMG-CoA reductase, the rate-limiting enzyme in the cholesterol synthesis pathway. This is a foundational pharmacology fact; content in this category should be reviewed by a qualified physician/educator before publishing.

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