[NEEDS EXPERT REVIEW] Which class of drugs works primarily by inhibiting the enzyme HMG-CoA reductase?
Difficulty: Medium
About this MCQ
Medium USMLE item. Correct choice: A. Statins.
- A. Statins ✓
- B. Beta-blockers
Why not B: “Beta-blockers” is not Statins.
- C. ACE inhibitors
Why not C: “ACE inhibitors” is not Statins.
- D. Diuretics
Why not D: “Diuretics” is not Statins.
Correct answer
A. Statins
Explanation
Statins (e.g., atorvastatin, simvastatin) lower cholesterol synthesis by inhibiting HMG-CoA reductase, the rate-limiting enzyme in the cholesterol synthesis pathway. This is a foundational pharmacology fact; content in this category should be reviewed by a qualified physician/educator before publishing.
Source: Original practice question, MCQsHub
Tags: American Exams, USMLE, Pharmacology, Needs Review
Submitted by: MCQsHub Editorial
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